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Influenza Virus Essay

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DESCRIPTION OF ORGANISM

Influenza is one of the most deadly viruses dating back to 1510 causing pandemics and endemic outbreaks all the way through 2013. The classifications of the influenza strains are known as A, B, and C with different subtypes HA and NA. Influenza A virions have close to 500 HA and NA spikes sticking out of the lipid bilayer characterized by 4 main proteins HA, NA, M2 and M1. Influenza type B has quite a few similarities to type A, but encodes proteins differently in the NB and MB2 protein membrane where type C differentiates where the ion channel is CM2, and instead of having two different glycoproteins type C has a multifunctional glycoprotein HA-esterase fusion. The influenza viruses usually have a spherical shape with …show more content…
The entry within a cell requires receptor binding to occur on the cell membrane with HA, and this is considered fusion. Once the HA is able to bind and enter within the cell the replication process will occur. The entering virus travels from the cytoplasm of the epithelial cell towards the nucleus of the cell. The main purpose here is for the virus to release the RNA gene segments by unraveling for further replication with polymerase chemicals acting as the catalyst for duplication. Once hundreds upon thousands of gene segments are replicated using the epithelial cells own energy the duplicated RNA gene segments make their way from the nucleus back out to the cytoplasm. The development for new HA proteins and other proteins for the virus takes place, and the role NA has in this regard is to destroy the receptors cleaving sialic acid allowing for viruses to push through the cell membrane to further infect other cells. What are the symptoms for how the human body responds when this pathogen infects the respiratory

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